Oral Argument: Sublingual Findings Challenge Key Assumptions about BPA Exposure

bpa has been associated with numerous health effects from anxiety and hyperactivity, “deranged metabolism” and human infertility ( just to name a few ) and has been banned in infant formula packaging. new research on bpa challenges key risk assessment assumptions. namely, most risk models that are used to create “safe dose” recommendations assume most ingested bpa is absorbed in the small intestine and converted to less risky metabolites. turns out that “…bpa can be efficiently and very rapidly absorbed through the oral mucosa…” which means you’re getting exposed to more bpa that thought. the authors conclude, somewhat dryly, that “It is clear that our data suggesting that BPA bioavailability can be high should raise some questions and possibly lead some agencies to reconsider their risk analysis on BPA.” an important subtext of the shifting sands on bpa risk assessment models, “of 84,000 registered industrial chemicals in the united states, only about 200 have been tested.

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