"All seven people infected with bird flu in a cluster of Indonesian cases can be linked to other patients, according to disease trackers investigating possible human-to-human transmission of the H5N1 virus.
A team of international experts has been unable to find animals that might have infected the people, the World Health Organization said in a statement today. In one case, a 10-year- old boy who caught the virus from his aunt may have passed it to his father, the first time officials have seen evidence of a three-person chain of infection, an agency spokeswoman said. Six of the seven people have died."
Forbes Many Health Care Workers Won't Show Up in Flu Pandemic
"With many Americans worried about their safety should a flu pandemic occur, there's little reassurance from a survey that finds that close to half of U.S. public health-care workers would not show up for work if such a pandemic occurred."
""Forty-two percent of the health care workers surveyed said they would not respond in the event of a flu pandemic," said study co-author Dr. Daniel J. Barnett, an instructor at the Johns Hopkins University Center for Public Health Preparedness in Baltimore."
New York Times Doubt Cast on Stockpile of a Vaccine for Bird Flu
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"A bird flu vaccine being stockpiled by the government in preparation for a possible pandemic protects only about half the people who receive it, scientists are reporting. In addition, it must be given in such high doses that if a pandemic were to start soon, manufacturers could not begin to make enough vaccine for all who would need it.
A dose 12 times the amount used in a standard flu shot protected 54 percent of the people in a study being described today in The New England Journal of Medicine. That level of effectiveness is "poor to moderate at best," said Dr. Gregory A. Poland of the Mayo Clinic, who wrote an editorial accompanying the report."
redux [03.27.06]
New York Times Studies Suggest Avian Flu Pandemic Isn't Imminent
[requires 'free' registration]
"Two groups of researchers, in Japan and in Holland, say they have discovered why the avian flu virus is rarely if ever transmitted from one person to another.
The reason, the researchers propose, is that the cells bearing the type of receptor the avian virus is known to favor are clustered in the deepest branches of the human respiratory tract, keeping it from spreading by coughs and sneezes. Human flu viruses typically infect cells in the upper respiratory tract."
"According to a University of Wisconsin news release approved by Dr. Kawaoka, "The finding suggests that scientists and public health agencies worldwide may have more time to prepare for an eventual pandemic.""
Times Online Bird flu mutation 'adds to threat of human pandemic'
"THE virus that causes bird flu has split into two distinct genetic subgroups, widening the gene pool from which a form that could trigger a human pandemic might evolve.
An analysis of more than 300 samples of the H5N1 virus taken from humans and birds has revealed that its family tree has started to branch out in a way that could make it more threatening to people."
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